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Ingredients
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Mesquite BBQ Sauce
Meat and Rub
Finish and Serving
Method
Mesquite BBQ Sauce
Build sauce
Stir in 1 cup ketchup, 1 tablespoon apple cider vinegar, 3 tablespoons brown sugar, 1 tablespoon molasses, and 2 teaspoons Worcestershire sauce. Mix to combine.
Season and thin
Add 1 teaspoon mesquite liquid smoke, 1 teaspoon smoked paprika, 1 teaspoon ground cumin, 1 teaspoon black pepper, and 1.5 teaspoons kosher salt. Pour in 1/2 cup water to loosen the sauce and bring to a gentle simmer.
Simmer and finish
Reduce heat to low and simmer, partially covered, stirring occasionally, until sauce thickens slightly and flavors meld, about 12–15 minutes. Taste and adjust seasoning: add a pinch more salt, a dash of vinegar, or extra liquid smoke if desired. Remove from heat and let cool slightly. If you prefer a very smooth sauce, purée with an immersion blender or in a countertop blender until smooth.
Meat and Rub
Prep meat
Pat the 3 lb brisket flat or chuck roast dry with paper towels. Trim excess fat, leaving a thin fat cap for flavor (about 1/8 inch) if present.
Make rub
In a small bowl combine 2 teaspoons kosher salt, 2 teaspoons coarse black pepper, 1 teaspoon garlic powder, 1 teaspoon onion powder, and 1 tablespoon brown sugar. Mix thoroughly.
Season meat
Rub 1 tablespoon vegetable oil over the surface of the meat to help the rub adhere. Evenly coat the entire roast with the dry rub, pressing it into the surface.
Cook low and slow
For oven: Preheat oven to 275°F (135°C). Place the seared roast on a rack in a shallow roasting pan. Tent loosely with foil and roast until internal temperature reaches 195–205°F (90–96°C) for brisket-style tenderness, about 3 to 4 hours (time varies by size). For grill/smoker: Set smoker to 225–250°F (107–121°C) using fruit woods and a small amount of mesquite for smoke flavor; place roast on the grate and smoke until internal temperature is 195–205°F, about 4–6 hours. If using a gas/charcoal grill without smoker, set up for indirect cooking and add soaked mesquite wood chips in a smoker box or foil packet placed over coals.
Rest
When the roast reaches target temperature, remove from heat and let rest, loosely tented with foil, for 30–45 minutes. Resting allows juices to redistribute and the meat to become easier to slice.
Finish and Serving
Warm sauce
If desired, reheat 1/2 cup of the prepared Mesquite BBQ sauce in a small saucepan over low heat until warm. This is for finishing and serving.
Serve
Serve immediately with extra sauce on the side. Leftover meat keeps well refrigerated for 3–4 days and the sauce for up to 2 weeks refrigerated in a sealed container.