In a large bowl, combine the ground beef, garlic powder, onion powder, salt, black pepper, and Worcestershire sauce. Mix until just combined, being careful not to overwork the meat.

Form Patties

Divide the mixture into 4 equal portions and shape each portion into a patty about 3/4 inch thick. Use your thumb to make a slight indentation in the center of each patty to prevent it from puffing up while cooking.

Cooking the Patties

Preheat Grill or Pan

Preheat a grill or skillet over medium-high heat. If using a skillet, you may add a little oil to prevent sticking.

Cook Patties

Place the patties on the grill or skillet and cook for about 4-5 minutes on one side. Flip the patties and place a slice of cheddar cheese on top of each patty. Cook for an additional 3-4 minutes, or until the cheese is melted and the patties reach your desired doneness.

Assembling the Burgers

Prepare the Buns

Toast the burger buns on the grill or in a toaster until golden brown.

Add Toppings

On the bottom half of each bun, layer lettuce, a slice of tomato (sliced), a few slices of red onion, and pickles. Place the cooked patty with melted cheese on top.

Finish with Condiments

Spread ketchup, mustard, and mayonnaise on the top half of the bun, then place it on top of the assembled burger.