In a large bowl, combine the grass-fed ground beef with salt, black pepper, garlic powder, and onion powder. Mix gently with your hands until the ingredients are just combined. Do not overmix.

Form the Patties

Divide the beef mixture into four equal portions and shape each portion into a patty, about 3/4 inch thick. Make a slight indentation in the center of each patty to prevent puffing during cooking.

Preheat the Grill or Pan

Preheat your grill or a skillet over medium-high heat. If using a skillet, add a little oil to prevent sticking.

Cook the Patties

Place the patties on the grill or skillet. Cook for about 4-5 minutes on one side, then flip and cook for another 3-4 minutes for medium-rare doneness. If using cheese, add a slice on top during the last minute of cooking.

Toast the Buns (optional)

While the patties are cooking, you can toast the burger buns on the grill or in a toaster until golden brown.

Assemble the Burgers

Once cooked, place each patty on a bottom bun. Top with lettuce, tomato slices, ketchup, mustard, and the top bun.

Serve

Serve the burgers immediately while hot with your favorite sides.